Desorption/Ionization on self-Assembled Monolayer Surface (DIAMS) Evaluation of a New Matrix-Free Laser Desorption/Ionization method

ثبت نشده
چکیده

Liens [1] http://okina.univ-angers.fr/publications?f[author]=2635 [2] http://okina.univ-angers.fr/lionel.sanguinet/publications [3] http://okina.univ-angers.fr/publications?f[author]=259 [4] http://okina.univ-angers.fr/olivier.aleveque/publications [5] http://okina.univ-angers.fr/m.dias/publications [6] http://okina.univ-angers.fr/eric.levillain/publications [7] http://okina.univ-angers.fr/publications?f[author]=43 [8] http://okina.univ-angers.fr/publications/ua2221

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Nanoparticles for Selective Laser Desorption/Ionization in Mass Spectrometry

The selective desorption/ionization of analytes using nanomaterials is investigated using metallic nanoparticles. By replacing the sodium citrate capping of gold nanoparticles with self-assembled monolayers, we are able to both enhance analyte ionization and selectively capture analytes. Capping gold nanoparticles with a monolayer of 4-mercaptobenzoic acid enhances analyte ionization while grea...

متن کامل

Self-assembled monolayers for MALDI-TOF mass spectrometry for immunoassays of human protein antigens.

This paper reports a method that combines self-assembled monolayers with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to perform immunoassays on clinical samples. The immunosensors are prepared by immobilizing His-tagged protein G (or A) to a monolayer presenting the Ni2+ chelates, followed by immobilization of IgG antibodies with specificity for the intended ana...

متن کامل

Profiling Kinase Activities by Using a Peptide Chip and Mass SpectrometryThis work was supported by the National Science Foundation. D.-H.M. was supported by the Burroughs Wellcome Fund Interfaces Program.

Herein we describe a strategy that combines peptide chips with matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) to evaluate kinase activities rapidly and semi-quantitatively. We have already shown that monolayers of alkanethiolates on gold are wellsuited as substrates for MALDI-TOF MS, and could be used to measure enzyme activities and to perform hig...

متن کامل

Kinetics of Surface-Induced Dissociation of N(CH <Subscript>3 </Subscript>) <Stack> <Subscript>4 </Subscript> <Superscript>+ </Superscript> </Stack> and N(CD <Subscript>3 </Subscript>) <Stack> <Subscript>4 </Subscript> <Superscript>+ </Superscript> </Stack> Using Silicon Nanoparticle Assisted Laser Desorption/Ionization and Laser Desorption/Ionization

The implementation of surface-induced dissociation (SID) to study the fast dissociation kinetics (sub-microsecond dissociation) of peptides in a MALDI TOF instrument has been reported previously. Silicon nanoparticle assisted laser desorption/ionization (SPALDI) now allows the study of small molecule dissociation kinetics for ions formed with low initial source internal energy and without MALDI...

متن کامل

Rapid evaluation and screening of interfacial reactions on self-assembled monolayers.

This paper reports 16 chemical reactions for elaborating the structures of self-assembled monolayers (SAMs) of alkanethiolates on gold. This work takes advantage of matrix-assisted laser desorption/ionization and time-of-flight mass spectrometry (MALDI-TOF MS) to rapidly characterize the products and yields of reactions that occur with molecules attached to monolayers. The paper also describes ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017